Epidemics, Slavery, Massacres, and Indigenous Resistance 1492-1599
De Soto, in quest for slaves and gold, is driven from southeastern tribal lands
Timucua, Appalachia, Coosa, Mobile, Natchez, Tonkawa, Choctaw, and other southeastern tribal groups fight de Soto’s invasion. Spain had given de Soto license to “conquer, pacify, and people” the lands known as La Florida (Florida, Georgia, South Carolina, Tennessee, Alabama, Mississippi, and Louisiana). Once he reaches the Mobiles in Alabama, the Choctaw and Mobile conspire to drive him out and force the Spaniards to retreat, with de Soto injured.